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1

Phase II Study of Single Intraperitoneal Chemotherapy Followed by Systemic Chemotherapy for Gastric Cancer with Peritoneal Metastasis

Motohiro Imano, Atsushi Yasuda, Tatsuki Itoh, Takao Satou, Ying-Feng Peng, Hiroaki Kato, Masayuki Shinkai, Masahiro Tsubaki, Yasutaka Chiba, Takushi Yasuda, Haruhiko Imamoto, Shozo Nishida, Yoshifumi

Journal:

Journal of Gastrointestinal Surgery

Année:

2012

Langue:

english

Fichier:

PDF, 204 KB

english, 2012

2

Rebamipide suppresses 5-fluorouracil-induced cell death via the activation of Akt/mTOR pathway and regulates the expression of Bcl-2 family proteins

Tsubaki, Masanobu, Takeda, Tomoya, Asano, Ryo-ta, Matsuda, Tomoyuki, Fujimoto, Shin-ichiro, Itoh, Tatsuki, Imano, Motohiro, Satou, Takao, Nishida, Shozo

Journal:

Toxicology in Vitro

Année:

2017

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2017

3

A randomized phase II multicenter trial to explore efficacy of weekly intraperitoneal in comparison with intravenous paclitaxel administered immediately after gastrectomy to the patients with high risk of peritoneal recurrence: final results of the INPACT trial

Takahashi, Naoto, Kanda, Mitsuro, Yoshikawa, Takaki, Takiguchi, Nobuhiro, Fujitani, Kazumasa, Miyamoto, Katsufumi, Ito, Yuichi, Takayama, Osamu, Imano, Motohiro, Mitsumori, Norio, Sakamoto, Junichi, M

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2018

4

Infantile myofibromatosis of the triceps detected by prenatal sonography

Kubota, Akio, Imano, Motohiro, Yonekura, Takeo, Hirooka, Shinji, Nose, Keisuke, Oyanagi, Harumasa, Nakayama, Masahiro

Journal:

Journal of Clinical Ultrasound

Année:

1999

Langue:

english

Fichier:

PDF, 837 KB

english, 1999

5

Safety of intraperitoneal administration of paclitaxel after gastrectomy with en-bloc D2 Lymph node dissection

Motohiro Imano, Haruhiko Imamoto, Tatsuki Itoh, Takao Satou, Ying-Feng Peng, Atsushi Yasuda, Hiroaki Kato, Osamu Shiraishi, Masayuki Shinkai, Takushi Yasuda, Yoshifumi Takeyama, Kiyokata Okuno, Hitosh

Journal:

Journal of Surgical Oncology

Année:

2012

Langue:

english

Fichier:

PDF, 155 KB

english, 2012

6

Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma

Masashi Yanae, Masanobu Tsubaki, Takao Satou, Tatsuki Itoh, Motohiro Imano, Yuzuru Yamazoe, Shozo Nishida

Journal:

Journal of Experimental & Clinical Cancer Research

Année:

2011

Langue:

english

Fichier:

PDF, 896 KB

english, 2011

7

Increased Osteopontin-Positive Macrophage Expression in Colorectal Cancer Stroma with Synchronous Liver Metastasis

Motohiro Imano, Kiyokata Okuno, Tatsuki Itoh, Eizaburo Ishimaru, Takao Satou, Hitoshi Shiozaki

Journal:

World Journal of Surgery

Année:

2010

Langue:

english

Fichier:

PDF, 362 KB

english, 2010

8

An immunohistochemical study of osteopontin in hepatolithiasis

Akihiro Nakai, Motohiro Imano, Yoshifumi Takeyama, Hitoshi Shiozaki, Harumasa Ohyanagi

Journal:

Journal of Hepato-Biliary-Pancreatic Sciences

Année:

2008

Langue:

english

Fichier:

PDF, 430 KB

english, 2008

9

Involvement of osteopontin as a core protein in cholesterol gallstone formation

Hideaki Ichikawa, Motohiro Imano, Yoshifumi Takeyama, Hitoshi Shiozaki, Harumasa Ohyanagi

Journal:

Journal of Hepato-Biliary-Pancreatic Sciences

Année:

2009

Langue:

english

Fichier:

PDF, 299 KB

english, 2009

10

Expression of manganese superoxide dismutase in esophageal and gastric cancers

Ryo Izutani, Satoshi Asano, Motohiro Imano, Daisuke Kuroda, Michio Kato, Harumasa Ohyanagi

Journal:

Journal of Gastroenterology

Année:

1998

Langue:

english

Fichier:

PDF, 549 KB

english, 1998

11

Exercise increases neural stem cell proliferation surrounding the area of damage following rat traumatic brain injury

Tatsuki Itoh, Motohiro Imano, Shozo Nishida, Masahiro Tsubaki, Shigeo Hashimoto, Akihiko Ito, Takao Satou

Journal:

Journal of Neural Transmission

Année:

2011

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2011

12

Exercise inhibits neuronal apoptosis and improves cerebral function following rat traumatic brain injury

Tatsuki Itoh, Motohiro Imano, Shozo Nishida, Masahiro Tsubaki, Shigeo Hashimoto, Akihiko Ito, Takao Satou

Journal:

Journal of Neural Transmission

Année:

2011

Langue:

english

Fichier:

PDF, 556 KB

english, 2011

13

Edaravone Protects Against Apoptotic Neuronal Cell Death and Improves Cerebral Function After Traumatic Brain Injury in Rats

Tatsuki Itoh, Takao Satou, Shozo Nishida, Masahiro Tsubaki, Motohiro Imano, Shigeo Hashimoto, Hiroyuki Ito

Journal:

Neurochemical Research

Année:

2010

Langue:

english

Fichier:

PDF, 424 KB

english, 2010

14

Immunohistochemical Expression of Osteopontin in Gastric Cancer

Motohiro Imano, Takao Satou, Tatsuki Itoh, Kenichi Sakai, Eizaburo Ishimaru, Atsushi Yasuda, Ying-Feng Peng, Masayuki Shinkai, Fumiharu Akai, Takushi Yasuda, Haruhiko Imamoto, Kiyokata Okuno, Hiroyuki

Journal:

Journal of Gastrointestinal Surgery

Année:

2009

Langue:

english

Fichier:

PDF, 255 KB

english, 2009

15

(−)-Epigallocatechin-3-gallate Protects Against Neuronal Cell Death and Improves Cerebral Function After Traumatic Brain Injury in Rats

Tatsuki Itoh, Motohiro Imano, Shozo Nishida, Masahiro Tsubaki, Shigeo Hashimoto, Akihiko Ito, Takao Satou

Journal:

NeuroMolecular Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 720 KB

english, 2011

16

Case of adrenal lymphangioma with atypical lymphocytes in aspirate cytology

Takao Satou, Tadao Uesugi, Yuka Nakai, Yoshiyuki Hayashi, Motohiro Imano, Shigeo Hashimoto

Journal:

Diagnostic Cytopathology

Année:

2003

Langue:

english

Fichier:

PDF, 100 KB

english, 2003

17

Massive bleeding from multiple jejunal diverticula associated with an angiodysplasia: Report of a case

Shiro Kawamura, Muneyoshi Nishijima, Takeshi Yamamoto, Ken-ichi Sakai, Hisaya Hirai, Motohiro Imano, Michio Kato, Harumasa Ohyanagi

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 619 KB

english, 2000

18

Erratum to: Phase I clinical trial of vaccination with URLC10-derived peptide for patients with advanced esophageal cancer

Ishikawa, Hajime, Imano, Motohiro, Shiraishi, Osamu, Yasuda, Atsushi, Peng, Ying-Feng, Shinkai, Masayuki, Yasuda, Takushi, Imamoto, Haruhiko, Takeda, Kazuyoshi, Shiozaki, Hitoshi

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 94 KB

english, 2012

19

Phase I clinical trial of vaccination with URLC10-derived peptide for patients with advanced esophageal cancer

Ishikawa, Hajime, Imano, Motohiro, Shiraishi, Osamu, Yasuda, Atsushi, Peng, Ying-Feng, Shinkai, Masayuki, Yasuda, Takushi, Imamoto, Haruhiko, Takeda, Kazuyoshi, Shiozaki, Hitoshi

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 596 KB

english, 2012

20

Reduction of metastasis, cell invasion, and adhesion in mouse osteosarcoma by YM529/ONO-5920-induced blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathway

Masanobu Tsubaki, Takao Satou, Tatsuki Itoh, Motohiro Imano, Mitsuhiko Ogaki, Masashi Yanae, Shozo Nishida

Journal:

Toxicology and Applied Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2012

21

Expression of manganese superoxide disumutase influences chemosensitivity in esophageal and gastric cancers

Ryo Izutani, Michio Kato, Satoshi Asano, Motohiro Imano, Harumasa Ohyanagi

Journal:

Cancer Detection and Prevention

Année:

2002

Langue:

english

Fichier:

PDF, 279 KB

english, 2002

22

The regulation of liver regeneration by the plasmin/α2-antiplasmin system

Kiyotaka Okada, Shigeru Ueshima, Motohiro Imano, Kazuo Kataoka, Osamu Matsuo

Journal:

Journal of Hepatology

Année:

2004

Langue:

english

Fichier:

PDF, 430 KB

english, 2004

23

(−)-Epigallocatechin-3-gallate increases the number of neural stem cells around the damaged area after rat traumatic brain injury

Tatsuki Itoh,Motohiro Imano,Shozo Nishida…

Journal:

Journal of Neural Transmission

Année:

2012

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2012

24

Increased apoptotic neuronal cell death and cognitive impairment at early phase after traumatic brain injury in aged rats

Itoh, Tatsuki, Imano, Motohiro, Nishida, Shozo, Tsubaki, Masahiro, Mizuguchi, Nobuyuki, Hashimoto, Shigeo, Ito, Akihiko, Satou, Takao

Journal:

Brain Structure and Function (Anatomy and Embryology 1891-2006)

Année:

2013

Langue:

english

Fichier:

PDF, 915 KB

english, 2013

25

Peritoneal metastatic lesions of gastric cancer exhibit low expression of human epidermal growth factor receptor 2

Motohiro Imano, Takao Satou, Tatsuki Itoh, Atsushi Yasuda, Hiroaki Kato, Masayuki Shinkai, Ying-Feng Peng, Masahiro Tsubaki, Takushi Yasuda, Haruhiko Imamoto, Shozo Nishida, Yoshifumi Takeyama, Kiyoka

Journal:

Targeted Oncology

Année:

2012

Langue:

english

Fichier:

PDF, 183 KB

english, 2012

26

Overexpression of MDR1 and survivin, and decreased Bim expression mediate multidrug-resistance in multiple myeloma cells

Masanobu Tsubaki, Takao Satou, Tatsuki Itoh, Motohiro Imano, Makiko Komai, Minori Nishinobo, Megumi Yamashita, Masashi Yanae, Yuzuru Yamazoe, Shozo Nishida

Journal:

Leukemia Research

Année:

2012

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2012

27

Bisphosphonate- and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2

Tsubaki, Masanobu, Satou, Takao, Itoh, Tatsuki, Imano, Motohiro, Yanae, Masashi, Kato, Chisato, Takagoshi, Risa, Komai, Makiko, Nishida, Shozo

Journal:

Molecular and Cellular Endocrinology

Année:

2012

Langue:

english

Fichier:

PDF, 1.99 MB

english, 2012

28

Complete regression of recurrent esophageal carcinoma with reduced expression of glutathione S-transferase-π by treatment with continuous infusion of 5-fluorouracil and low-dose cisplatin infusion

Kazunari Tominaga, Tetsuo Arakawa, Motohiro Imano, Michio Kato, Yuko Hamaguchi, Toshio Watanabe, Osamu Takaishi, Yasuhiro Fujiwara, Takashi Fukuda, Kazuhide Higuchi, Harushi Osugi, Shinji Chono, Tetsu

Journal:

American Journal of Gastroenterology

Année:

1999

Langue:

english

Fichier:

PDF, 473 KB

english, 1999

29

High expression of epithelial cellular adhesion molecule in peritoneal metastasis of gastric cancer

Motohiro Imano, Tatsuki Itoh, Takao Satou, Atsushi Yasuda…

Journal:

Targeted Oncology

Année:

2013

Langue:

english

Fichier:

PDF, 257 KB

english, 2013

30

Treatment strategies for gastric cancer patients with peritoneal metastasis

Motohiro Imano, Kiyotaka Okuno

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 367 KB

english, 2014

31

Appearance of neural stem cells around the damaged area following traumatic brain injury in aged rats

Tatsuki Itoh, Motohiro Imano, Shozo Nishida…

Journal:

Journal of Neural Transmission

Année:

2013

Langue:

english

Fichier:

PDF, 2.24 MB

english, 2013

32

Inhibition of the tumour necrosis factor-alpha autocrine loop enhances the sensitivity of multiple myeloma cells to anticancer drugs

Tsubaki, Masanobu, Komai, Makiko, Itoh, Tatsuki, Imano, Motohiro, Sakamoto, Kotaro, Shimaoka, Hirotaka, Ogawa, Naoki, Mashimo, Kenji, Fujiwara, Daichiro, Takeda, Tomoya, Mukai, Junji, Sakaguchi, Katsu

Journal:

European Journal of Cancer

Année:

2013

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2013

33

Decreased preoperative plasma substance P concentration is likely associated with postoperative silent aspiration after esophagectomy

Yasuda, Takushi, Nakamori, Yasuhiro, Shiraishi, Osamu, Yasuda, Atsushi, Peng, Ying-Feng, Shinakai, Masayuki, Imano, Motohiro, Imamoto, Haruhiko, Shiozaki, Hitoshi

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 322 KB

english, 2014

34

Phase I clinical trial of vaccination with LY6K-derived peptide in patients with advanced gastric cancer

Ishikawa, Hajime, Imano, Motohiro, Shiraishi, Osamu, Yasuda, Atsushi, Peng, Ying-Feng, Shinkai, Masayuki, Yasuda, Takushi, Imamoto, Haruhiko, Shiozaki, Hitoshi

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2014

35

Activation of NF-κB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines

Tsubaki, Masanobu, Komai, Makiko, Fujimoto, Shin-ichiro, Itoh, Tatsuki, Imano, Motohiro, Sakamoto, Kotaro, Shimaoka, Hirotaka, Takeda, Tomoya, Ogawa, Naoki, Mashimo, Kenji, Fujiwara, Daiichiro, Mukai,

Journal:

Journal of Experimental & Clinical Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 548 KB

english, 2013

36

By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells

Tsubaki, Masanobu, Komai, Makiko, Itoh, Tatsuki, Imano, Motohiro, Sakamoto, Kotaro, Shimaoka, Hirotaka, Takeda, Tomoya, Ogawa, Naoki, Mashimo, Kenji, Fujiwara, Daiichiro, Mukai, Junji, Sakaguchi, Kats

Journal:

Leukemia Research

Année:

2014

Langue:

english

Fichier:

PDF, 2.20 MB

english, 2014

37

Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway

Tsubaki, Masanobu, Itoh, Tatsuki, Satou, Takao, Imano, Motohiro, Komai, Makiko, Ogawa, Naoki, Mukai, Junji, Nishida, Shozo

Journal:

Biochemical Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2013

38

Double-blind, placebo-controlled, randomized phase II study of TJ-14 (hangeshashinto) for gastric cancer chemotherapy-induced oral mucositis

Aoyama, Toru, Nishikawa, Kazuhiro, Takiguchi, Nobuhiro, Tanabe, Kazuaki, Imano, Motohiro, Fukushima, Ryoji, Sakamoto, Junichi, Oba, Mari S., Morita, Satoshi, Kono, Toru, Tsuburaya, Akira

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 220 KB

english, 2014

39

Dimethyl fumarate induces apoptosis of hematopoietic tumor cells via inhibition of NF-κB nuclear translocation and down-regulation of Bcl-xL and XIAP

Tsubaki, Masanobu, Ogawa, Naoki, Takeda, Tomoya, Sakamoto, Kotaro, Shimaoka, Hirotaka, Fujita, Arisa, Itoh, Tatsuki, Imano, Motohiro, Satou, Takao, Nishida, Shozo

Journal:

Biomedicine & Pharmacotherapy

Année:

2014

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2014

40

Complete regression of recurrent esophageal carcinoma with reduced expression of glutathione S-transferase-pi by treatment with continuous infusion of 5-fluorouracil and low-dose cisplatin infusion

Tominaga, Kazunari, Arakawa, Tetsuo, Imano, Motohiro, Kato, Michio, Hamaguchi, Yuko, Watanabe, Toshio, Takaishi, Osamu, Fujiwara, Yasuhiro, Fukuda, Takashi, Higuchi, Kazuhide, Osugi, Harushi, Chono, S

Journal:

American Journal of Gastroenterology

Année:

1999

Langue:

english

Fichier:

PDF, 473 KB

english, 1999

41

Overexpression of survivin via activation of ERK1/2, Akt, and NF-κB plays a central role in vincristine resistance in multiple myeloma cells

Tsubaki, Masanobu, Takeda, Tomoya, Ogawa, Naoki, Sakamoto, Kotaro, Shimaoka, Hirotaka, Fujita, Arisa, Itoh, Tatsuki, Imano, Motohiro, Ishizaka, Toshihiko, Satou, Takao, Nishida, Shozo

Journal:

Leukemia Research

Année:

2015

Langue:

english

Fichier:

PDF, 1.91 MB

english, 2015

42

A newly modified esophagogastrostomy with a reliable angle of His by placing a gastric tube in the lower mediastinum in laparoscopy-assisted proximal gastrectomy

Yasuda, Atsushi, Yasuda, Takushi, Imamoto, Haruhiko, Kato, Hiroaki, Nishiki, Kohei, Iwama, Mitsuru, Makino, Tomoki, Shiraishi, Osamu, Shinkai, Masayuki, Imano, Motohiro, Furukawa, Hiroshi, Okuno, Kiyo

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2015

43

Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation

Tsubaki, Masanobu, Komai, Makiko, Itoh, Tatsuki, Imano, Motohiro, Sakamoto, Kotaro, Shimaoka, Hirotaka, Takeda, Tomoya, Ogawa, Naoki, Mashimo, Kenji, Fujiwara, Daiichiro, Mukai, Junji, Sakaguchi, Kats

Journal:

Journal of Biomedical Science

Année:

2014

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2014

44

Phase II Study of a Combination of Irinotecan and S-1 in Patients with Advanced Gastric Cancer (OGSG0002)

Uedo, Noriya, Narahara, Hiroyuki, Ishihara, Ryu, Takiuchi, Hiroya, Goto, Masahiro, Fujitani, Kazumasa, Hirao, Motohiro, Tsujinaka, Toshimasa, Imano, Motohiro, Furukawa, Hiroshi, Tsukuma, Hideaki, Tagu

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 147 KB

english, 2007

45

Statins inhibited the MIP-1α expression via inhibition of Ras/ERK and Ras/Akt pathways in myeloma cells

Tsubaki, Masanobu, Mashimo, Kenji, Takeda, Tomoya, Kino, Toshiki, Fujita, Arisa, Itoh, Tatsuki, Imano, Motohiro, Sakaguchi, Katsuhiko, Satou, Takao, Nishida, Shozo

Journal:

Biomedicine & Pharmacotherapy

Année:

2016

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2016

46

RANK-RANKL interactions are involved in cell adhesion-mediated drug resistance in multiple myeloma cell lines

Tsubaki, Masanobu, Takeda, Tomoya, Yoshizumi, Misako, Ueda, Emi, Itoh, Tatsuki, Imano, Motohiro, Satou, Takao, Nishida, Shozo

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 2.49 MB

english, 2016

47

Phase II study of S-1 monotherapy in patients over 75 years of age with advanced gastric cancer (OGSG0404)

Imamura, Hiroshi, Kishimoto, Tomono, Takiuchi, Hiroya, Kimura, Yutaka, Morimoto, Takashi, Imano, Motohiro, Iijima, Shohei, Yamashita, Keishi, Maruyama, Kentaro, Otsuji, Toshio, Kurokawa, Yukinori, Fur

Journal:

Journal of Chemotherapy

Année:

2014

Langue:

english

Fichier:

PDF, 135 KB

english, 2014

48

Feasibility of weekly intraperitoneal versus intravenous paclitaxel therapy delivered from the day of radical surgery for gastric cancer: a preliminary safety analysis of the INPACT study, a randomized controlled trial

Kodera, Yasuhiro, Takahashi, Naoto, Yoshikawa, Takaki, Takiguchi, Nobuhiro, Fujitani, Kazumasa, Ito, Yuichi, Miyamoto, Katsufumi, Takayama, Osamu, Imano, Motohiro, Kobayashi, Daisuke, Miyashita, Yumi,

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 433 KB

english, 2017

49

Mangiferin induces apoptosis in multiple myeloma cell lines by suppressing the activation of nuclear factor kappa B-inducing kinase

Takeda, Tomoya, Tsubaki, Masanobu, Kino, Toshiki, Yamagishi, Misa, Iida, Megumi, Itoh, Tatsuki, Imano, Motohiro, Tanabe, Genzoh, Muraoka, Osamu, Satou, Takao, Nishida, Shozo

Journal:

Chemico-Biological Interactions

Année:

2016

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2016

50

PKC/MEK inhibitors suppress oxaliplatin-induced neuropathy and potentiate the antitumor effects

Tsubaki, Masanobu, Takeda, Tomoya, Tani, Tadahumi, Shimaoka, Hirotaka, Suzuyama, Naohiro, Sakamoto, Kotaro, Fujita, Arisa, Ogawa, Naoki, Itoh, Tatsuki, Imano, Motohiro, Funakami, Yoshinori, Ichida, Se

Journal:

International Journal of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 654 KB

english, 2015